What is a requirement for filling a prescription for Clozapine?

Clozapine is an atypical antipsychotic medication used primarily for treatment-resistant schizophrenia. Because of the risk of serious side effects, particularly agranulocytosis (a potentially life-threatening decrease in the number of white blood cells), there are strict regulations governing its prescription and dispensing.

A requirement for filling a prescription for Clozapine includes obtaining a Pre-dispense Authorization Code. This code is necessary to ensure that the pharmacy has verified the patient's white blood cell counts and that safety monitoring protocols are being followed. The code confirms compliance with the monitoring requirements mandated by the FDA and the Clozapine Risk Evaluation and Mitigation Strategy (REMS) program.

This safety protocol is critical in preventing adverse effects and ensuring proper patient care. Therefore, obtaining a Pre-dispense Authorization Code stands out as an essential requirement for filling a Clozapine prescription.