How frequently must blood work be conducted for new patients taking Clozapine?

For new patients starting on Clozapine, blood work is required weekly during the initial treatment phase. This is crucial because Clozapine can cause agranulocytosis, a potentially severe side effect that results in a dangerously low white blood cell count. By monitoring the patient's blood weekly, healthcare providers can ensure that the patient's white blood cell counts remain within a safe range and identify any adverse effects early on.

Once a patient has stabilized and has shown a consistent safe white blood cell count for a specified period, the frequency of blood monitoring can be reduced. However, during the initial weeks of treatment, the weekly monitoring is essential to mitigate risks associated with this powerful antipsychotic medication. This protocol underscores the importance of safety and careful management in patients who are being treated with Clozapine, particularly when they are first starting the medication.